Drug stability

Drug stability

Choosing the Right Receptor Medium for IVRT and IVPT Studies

Choosing the Right Receptor Medium for IVRT and IVPT Studies

In vitro release testing (IVRT) and in vitro permeation testing (IVPT) are widely used to characterize topical and transdermal drug products throughout formulation development, quality assessment, and comparative performance studies. While parameters such as membrane selection, diffusion cell configuration, sampling intervals, and temperature control receive considerable attention, one experimental factor has an equally important influence […]
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Excipient Screening vs Excipient Synthesis: Which Problem Are You Actually Solving?

Excipient Screening vs Excipient Synthesis: Which Problem Are You Actually Solving?

Excipients play a fundamental role in pharmaceutical formulation development, influencing manufacturability, stability, drug release, bioavailability, patient acceptability, and overall product performance. Although many pharmaceutical products can be successfully developed using commercially available excipients, certain formulation challenges cannot always be resolved through conventional excipient selection alone. When formulation performance does not meet predefined development objectives, scientists […]
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